EVERYTHING IS GOING SWIMMINGLY: How Well Does the Monkeypox Vax Work? No One Knows for Sure: Health officials hang hopes on Jynneos, but vaccine not yet proven to protect against infection.
One number that’s been unquestionably quoted by various media organizations — “85% effective” or “at least 85% effective” — is based entirely on a small study done in Africa in the 1980s that has major limitations. One data expert calls its findings “pretty weak.” Other studies have only been conducted in animals.
Still, “I’ve heard from many folks in the community that they expect almost no risk of becoming infected 2 weeks after their first shot,” said Michael Donnelly, MSc, a New York City data scientist and LGBT health advocate, in an interview with MedPage Today. “Or they think they won’t get any symptoms if they were exposed before their shot.”
The lack of accurate information about the vaccine is “a big problem,” Jay Varma, MD, director of the Cornell Center for Pandemic Prevention and Response in New York, said in an interview. “It is absolutely critical that public health officials work on messaging this uncertainty to people being vaccinated.”
The Covid track record doesn’t inspire confidence, but at least they’re admitting there’s a problem.
Plus:
To make matters more complicated, the new outbreak is quite different from those in the past. This time, the virus appears to largely be transmitted through sexual rather than other kinds of contact, with an overwhelming majority of cases among men who have sex with men. (There’s now a debate in the medical world over whether to refer to monkeypox as a sexually transmitted disease [STD].) Previous outbreaks in Africa appeared to have been spread in households by various routes.
“The vaccine was evaluated on the assumption that most or all exposures would be from skin-to-skin contact,” Varma told MedPage Today. “The head of the penis and interior of the anus may have characteristics that make them more susceptible to infection such as a lower dose of virus needed, less abundant antibodies or other components of the immune system, or concurrent STDs increasing risk. It’s possible that the level of protection may be the same, but we should not assume it’s the same without evaluating it.”
Like I say, at least they’re admitting to uncertainties here.