THEY’RE VERY DESTRUCTIVE TO CONNECTIVE TISSUE: FDA warns of fluoroquinolone antibiotics tied to deadly heart vessel tears. “Fluoroquinolones have been a mainstay of antibiotic therapy, particularly for upper respiratory conditions, and have been around for more than three decades. They include Cipro (ciprofloxacin), Levaquin (levofloxacin), Factive, (gemifloxacin), and Avelox ( moxifloxacin).”

I’ve taken Cipro with no issues, but I took Levaquin for a stubborn sinus infection a few years ago and had muscle soreness for a couple of months; it made it hard to work out seriously. I wouldn’t take it again for anything less than life-threatening.