METFORMIN UPDATE: Diabetes drug Metformin may fight heart disease, study says. “Metformin could reverse left ventricular hypertrophy, thickening of the heart muscle, which can cause heart disease, according to research published Tuesday in the European Heart Journal. . . . ‘The findings from our study reinforce the notion that metformin has the potential to improve cardiovascular health, offering the possibility of improving life expectancy of patients,’ Lang said. ‘From the standpoint of clinical practice, this drug is already approved and well tolerated with minimal side effect.'”