HOW TO LOSE 132 POUNDS OVERNIGHT: Doctors Remove 132-Pound Ovarian Tumor From Patient, One of the Largest Ever of Its Kind. “The tumor was removed in a single surgery that lasted five hours and which required the expertise of nearly 25 highly skilled specialists. The patient first sought medical help after she began to rapidly gain weight at a rate of nearly 10 pounds a week, Danbury Hospital reported in a statement. A scan revealed that the source of the rapid weight gain was a tumor of shocking size.”