GOOD: New Drug for Severe Eczema Is Successful in 2 New Trials. “Most patients who got the active drug, dupilumab, instead of a placebo reported that the itching began to wane within two weeks and was gone in a few months, as their skin began to clear. Nearly 40 percent of participants getting the drug saw all or almost all of their rash disappear. For some, relief was almost instantaneous.”