January 12, 2012

RESVERATROL AND RESEARCH FRAUD: Not sure how much, if at all, this undercuts the basic resveratrol claim but I’m going to see if I can find out more.

UPDATE: Lots of thoughts on what this means from Derek Lowe. “Now for the last big issue: what does this do to the whole resveratrol/sirtuin field? Not as much as you might think. As mentioned above, Das really doesn’t seem to have been that big a figure in it, despite cranking out the publications, and a lot of interesting (although often confusing) work has come from a variety of other labs. The people who did this study in humans, for example, are (to the best of my knowledge) above reproach. But (as that post shows in its various links), there’s a lot of conflicting data about resveratrol in animal models. The whole topic is deeply confusing. But this UConn/Das business does not help clear anything up, not at all – it’s a big bucket of mud and slop dumped into the tank, which is just what we didn’t need.”

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