Archive for 2017

SALENA ZITO: THIS IS THE NEXT DEMOCRATIC STRONGHOLD TO CRACK LIKE THE RUST BELT.

As Zito accurately writes, first class in an Amtrak Acela Express on the Northeast Corridor is “a jarring anthropological experience — that is, if you bother to look up from your digital device. Not because it is too fast, or the curves are too sharp; the jarring effect comes from the visual decay of our country swooshing right before your eyes.”

Read the whole thing.

UPDATE (FROM GLENN): In the comments: “President Trump may not be able to fix the carnage. But he was elected because he is the only politician in America willing to admit the carnage is happening.”

BYRON YORK: Senate committee targets FBI No. 2 in Trump dossier probe.

Sen. Charles Grassley, chairman of the Senate Judiciary Committee, has sent a letter to FBI Director James Comey demanding the story behind the FBI’s reported plan to pay the author of a lurid and unsubstantiated dossier on candidate Donald Trump. In particular, Grassley appears to be zeroing in on the FBI’s deputy director, Andrew McCabe, indicating Senate investigators want to learn more about McCabe’s role in a key aspect of the Trump-Russia affair.

Grassley began his investigation after the Washington Post reported on February 28 that the FBI, “a few weeks before the election,” agreed to pay former British spy Christopher Steele to investigate Trump. Prior to that, supporters of the Hillary Clinton presidential campaign had paid Steele to gather intelligence on Clinton’s Republican rival. In the end, the FBI did not pay Steele, the Post reported, after the dossier “became the subject of news stories, congressional inquiries and presidential denials.” It is not clear whether Steele worked under agreement with the FBI for any period of time before the payment deal fell through.

“The idea that the FBI and associates of the Clinton campaign would pay Mr. Steele to investigate the Republican nominee for president in the run-up to the election raises further questions about the FBI’s independence from politics, as well as the Obama administration’s use of law enforcement and intelligence agencies for political ends,” Grassley wrote in a letter to Comey dated March 28.

Raises questions, answers questions, whatever.

JONATHAN HAIDT ON THE CULTURAL ROOTS OF CAMPUS RAGE:

When a mob at Vermont’s Middlebury College shut down a speech by social scientist Charles Murray a few weeks ago, most of us saw it as another instance of campus illiberalism. Jonathan Haidt saw something more—a ritual carried out by adherents of what he calls a “new religion,” an auto-da-fé against a heretic for a violation of orthodoxy.

“The great majority of college students want to learn. They’re perfectly reasonable, and they’re uncomfortable with a lot of what’s going on,” Mr. Haidt, a psychologist and professor of ethical leadership at New York University’s Stern School of Business, tells me during a recent visit to his office. “But on each campus there are some true believers who have reoriented their lives around the fight against evil.”

These believers are transforming the campus from a citadel of intellectual freedom into a holy space—where white privilege has replaced original sin, the transgressions of class and race and gender are confessed not to priests but to “the community,” victim groups are worshiped like gods, and the sinned-against are supplicated with “safe spaces” and “trigger warnings.”

The fundamentalists may be few, Mr. Haidt says, but they are “very intimidating” since they wield the threat of public shame. On some campuses, “they’ve been given the heckler’s veto, and are often granted it by an administration who won’t stand up to them either.”

Yes, the crybullies are a small minority even on most lefty campuses. But they’ve been unrestrained because the administration, basically, supports them. Plus:

Down the hall from Mr. Haidt’s office, I noticed a poster advertising a “bias response hotline” students can call “to report an experience of bias, discrimination or harassment.” I joke that NYU seems to have its own version of the morality police in Islamic countries like Saudi Arabia. “It’s like East Germany,” Mr. Haidt replies—with students, at least some of them, playing the part of the Stasi.

How did we get here, and what can be done? On the first question, Mr. Haidt points to a braided set of causes. There’s the rise in political polarization, which is related to the relatively recent “political purification of the universities.” While the academy has leaned left since at least the 1920s, Mr. Haidt says “it was always just a lean.” Beginning in the early 1990s, as the professors of the Greatest Generation retired, it became a full-on tilt.

“Now there are no more conservative voices on the faculty or administration,” he says, exaggerating only a little. Heterodox Academy cites research showing that the ratio of left to right professors in 1995 was 2 to 1. Now it is 5 to 1.

The left, meanwhile, has undergone an ideological transformation.

At the very moment where higher education is in trouble, it is dominated by a mindset that sets it in opposition to the mainstream culture. This will end well:

“People are sick and tired of being called racist for innocent things they’ve said or done,” Mr. Haidt observes. “The response to being called a racist unfairly is never to say, ‘Gee, what did I do that led to me being called this? I should be more careful.’ The response is almost always, ‘[Expletive] you!’ ”

He offers this real-world example: “I think that the ‘deplorables’ comment could well have changed the course of human history.”

I certainly hope so.

ME, FIVE YEARS AGO, ON FAITH IN SCIENCE: “Regardless, while one should trust science as a method — honestly done, science remains the best way at getting to the truth on a wide range of factual matters — there’s no particular reason why one should trust scientists and especially no particular reason why one should trust the people running scientific institutions, who often aren’t scientists themselves.”

OF COURSE THEY DO: Minimum Wage Activists Call Tipping Racist. “However, there is little historical evidence for the argument.”

When has that ever stopped them before?

DRUDGE: Trump Should Do An Interview With Oprah.

President Trump should expand his media presence beyond Twitter and do an interview with Oprah Winfrey, Matt Drudge suggested Friday.

“I would sit down and give an interview with Oprah,” Drudge said on “The Savage Nation” radio show. “Do you know in the ’80s he did and she melted in his presence? The audience of women melted in his presence.”

“Now, that doesn’t mean he changes his policies … but why not do a little bit more to reach out to the other half?” he added.

Drudge said that Twitter “feeds the junkies” and caters to a small group of people, but by setting up an interview with the talk show star, Trump could reach a larger audience and do more to sell his political agenda.

So long as it turns out better than his interview with Connie Chung. “There was a level of unprofessionalism. It was like you’re being interviewed by a child.”

I DO WORRY ABOUT THAT: Is the Cure for Aging Just Around the Corner? Here’s hoping that we’ve not been born one generation too early.

Peter de Keizer, a molecular geneticist at Erasmus University, reports in the journal Cell that he and his colleagues have developed a technique that kills off senescent cells. Our bodies have two ways of preventing damaged cells from becoming cancerous: kill them off, or cause them to cease replication and thus become senescent. Senescent cells accumulate as we grow older, secreting inflammatory substances that harm neighboring cells and contribute to many age-related diseases, including atherosclerorsis and diabetes.

De Keizer and his colleagues have developed a treatment in mice that selectively kills senescent cells while leaving healthy normal cells alone. They discovered that old or damaged cells become senescent rather than die when the FOXO4 protein binds to the tumor suppressor gene p53. They have designed another protein that interferes with the ability of FOXO4 to halt p53 from causing cells to die.

De Keizer’s team administered the new protein to both fast-aging and normally aged mice. The treatment worked as they had hoped, jumpstarting the ability of p53 to make senescent cells commit suicide. Eliminating senescent cells restored stamina, fur density, and kidney function in both strains of mice. The researchers report that they are continuing to study the rodents to see if the treatment extends their lifespans. They plan to try the treatment to stop brain cancer in human beings, but the ultimate goal is to treat aging as a disease. “Maybe when you get to 65 you’ll go every five years for your anti-senescence shot in the clinic. You’ll go for your rejuvenation shot,” de Keizer told the Tech Times.

In the same week, another group of Harvard researchers led by molecular biologist David Sinclair reported in Science about experiments in mice that thwart DNA damage associated with aging and exposure to radiation. As we age, our cells lose their ability to repair the damage to the DNA that makes up our genes. The repair process is orchestrated by the SIRT1 and PARP1 proteins. Both proteins consume the ubiquitous coenzyme nicotinamide adenine dinucleotide (NAD) to operate. As we grow older, the amount of NAD in our cells declines, thus allowing another protein, DBC1, to inhibit the DNA repair activity of both SIRT1 and PARP1.

I’m taking Niagen, which contains the NAD precursor nicotinamide riboside. How well does it work? I have no side effects that I can identify, and my workouts seem to have been more productive since I started taking it, but really there’s no way to tell if it’s slowing aging or not.