Archive for 2012

RETIREMENT PLANNING: You should plan to live to be 100 years old.

My take on the mortality tables: they are excessively pessimistic. The mortality tables assume a fairly static biomedical treatment environment in which only small incremental improvements to medical care are possible. No discontinuities are part of the forecast. This seems a very big mistake. On the horizon we can see the approach of effective gene therapies, cell therapies, and other treatments that attack the underlying mechanisms of aging. The scientists doing research on these treatments will succeed. Once they do we will have biotechnology that enables us to repair aged tissue.

For a long time mortality has declined fairly slowly. That’s because we’ve had no tools for attacking the underlying mechanisms of aging. Our bodies gradually wear out just like bodies 50 or 100 years ago. We’ve got medical treatments that reduce the consequences of failing tissue (e.g. blood pressure medicine) and treatments that slow the rate of development of some types of problems (e.g. cholesterol lowering drugs). But we can’t do much about the rate at which we accumulate mutations or the rate at which a href=”http://www.futurepundit.com/archives/008684.html”>we accumulate toxic intracellular junk.

We aren’t going to stay helpless against aging tissues. The legions of scientists experimenting with pluripotent stem cells, tissue engineering, gene therapies, and other promising therapies will succeed and they will succeed in the first half of the 21st century. Once we can fix and replace failing parts the mortality tables go out the windows as we gain the ability to do what we can now do to old cars: replace parts and keep on going. At some point in the 21st century we will reach actuarial escape velocity where the rate at which we can repair the body exceeds the rate at which pieces of the body wear out and fail. Our rejuvenated bodies will then go on for many more decades and eventually centuries.

In a nutshell: If you are in your 30s or below I think your odds of dying of old age are remote. Whether folks in their 40s, 50s, and beyond will live to benefit from rejuvenation therapies probably depends on how long they will live naturally. Someone who is 50 years old and has 40 years to go even without biomedical advances will certainly live long enough to enjoy the benefits of biotechnologies that will enable them to live well beyond 90 years.

Let’s hope.

HOW’S THAT HOPEY-CHANGEY STUFF WORKIN’ OUT FOR YA? (CONT’D): Is 8% Unemployment “The New Normal?” “Or perhaps it’s wishful thinking to believe that the number will stay that low.”

BE THANKFUL AND KNOW YOUR PLACE, citizen. The entitled attitude one encounters among public employees these days is certainly not limited to law enforcement, but it’s most troubling there.

ON TWITTER, TERRY TEACHOUT REMINDS US THAT IT’S LOUIS ARMSTRONG’S BIRTHDAY. In observation of that august date, I recommend Charles Black’s My World With Louis Armstrong. Black wrote the brief in Brown v. Board of Education with Thurgood Marshall. This essay helps explain why.

SHOULD YOU TAKE ANTIBIOTICS? Theodore Dalrymple on the ups and downs. “Only those who can relive, either in their memory or imagination (which is much rarer), what it was like to be ill in the pre-antibiotic era can appreciate the rapture with which the development of antibiotics was greeted.”

READER BOOK PLUG: Reader David Welch writes: “I’m a long-time reader of Instapundit and have noticed you occasionally linking to e-books written by your readers. I am writing to ask if you’d consider linking to a novel I have for sale on Amazon. It is an action-adventure/crime thriller by the name of Slade Masters.” Done!

REPEAL THE HOLLYWOOD TAX CUTS! Reader Theodore Simon writes: “Never mind putting back the old excise tax on films. Just don’t let Congress extend the generous tax write-offs that are written for Hollywood’s benefit into Section 181 of the IRC, which allows film makers to expense rather than amortize certain production costs and is the motion picture industry’s equivalent of the oil industry’s depletion allowance. HR 5793 would extend those tax write-off provisions for another two years. They were supposed to lapse at the end of 2011.”

WALTER RUSSELL MEAD: The Real Information Revolution. “Don’t misunderstand: We think social media are fun. But innovation that changes the way business works is far more important.”

JOHN HINDERAKER: Is Obama Slipping? “Given that actions speak louder than words, one thing you can do is look at where the candidates are spending their money: nearly all of Obama’s campaign spending (and Romney’s too) is directed at states that Obama carried in 2008. This means that notwithstanding the media cheerleading, Obama is playing defense, not offense.”

“IT’S JUST THE WAR, AND THAT LYING SON-OF-A-BITCH JOHNSON:” Life Imitates Forrest Gump.