Archive for 2008

JERRY POURNELLE: “Apparently Newt has stopped reading me. I’ll have to see if I can fix that.”

IF YOU MISSED IT ON XM SATELLITE RADIO EARLIER TONIGHT, you can listen to PJM Political online.

DO YOU NEED A NIKON D300? No. I love the camera, as I said. But, as I also said, the other digital SLRs are great cameras, too. To prove it, here’s a picture from reader Patrick Wilson, taken with a Nikon D70 and the same 18-200 VR lens that I use a lot. (Click the image for a bigger version).

greenlizard.jpg

SWEET CAMPAIGN CASH: “So the $10M figure, according to the Clinton campaign, is not a goal. It is, indeed, cash in the bank.”

ORIN KERR HAS an interesting post on Virginia v. Moore, and I’m also pleased to note that my colleague Tom Davies’ work on the original meaning of the Fourth Amendment was repeatedly mentioned by the Court.

ESPIONAGE OR PETTY THEFT? Which is more embarrassing for Mexico? “Whether he was up to no good or simply desperate to play BrickBreaker, a Mexican press attaché was caught on camera by Secret Service pocketing several White House BlackBerries during a recent meeting in New Orleans.”

TALKLEFT: “I also understand why Obama is dissing the Netroots now. They will never criticize him anyway. Why should he pander to them then?”

RESVERATROL UPDATE: Glaxo has bought Sirtris, the company with an arsenal of SIRT-1 drugs that do what resveratrol does only more so.

UPDATE: More thoughts from Derek Lowe on what it means. “It’s still a long shot, but it’s one of the most intriguing ones in the history of medicine. Actually, from one perspective, you wonder how long a shot it is: a biochemical pathway that seems to extend healthy life in yeast, roundworms, flies, and mice would seem to have some odds of doing the same thing in man. A lot of drug programs have been started with a lot less backing them up, albeit for rather less earth-shattering indications. . . . a drug for aging is a perfect example of something the FDA has absolutely no idea of how to approach. Well, it’s not just the FDA, come to think of it: how on earth would you design a Phase II trial for life extension? How long would it take?”

Plus, Leon Kass will be unhappy.

UPDATE: Reader John Coleman emails:

The founders of Sirtris spoke to my class at Harvard Business School last week. They were extremely impressive, and, from a business standpoint, I would say this series of drugs is not as long a shot as
some people think. I’m not a scientist, so I don’t know the extent to which the drugs effects will transfer from mice to humans; but the firm is well run and the people in it have a great deal of faith in the power of resveratrol across a number of condititions.

There is a brand new Harvard Business School case available on Sirtris (we read it last week), but its not up on the HBS Press website yet. When it’s made available, I’d recommend you read it — it’s probably
the best layman’s guide to the company and the science around.

I look forward to its publication.

WHAT AMERICA NEEDS IS A GOOD 1 cent cell phone.

Well, possibly.

DEMOCRATS BACKING OFF HEALTHCARE REFORM? “The trouble of course is that lots of people are satisfied with their healthcare.”

VICTIMS OF ALLITERATION. A new Fox show going after “deadbeat dads.”

“And what about deadbeat moms? Is anyone going after them?” They’re too close to the audience demographic, I’d guess.

THOUGHTS ON PHIL BREDESEN as a potential Obama running mate. This relates to some earlier thoughts of mine, though I don’t think Bredesen’s last couple of years have been as good as the ones that preceded them.

ED DRISCOLL: I hate Illinois Nazis. Yeah, me too, when I’m not too busy laughing at them. It’s a fine line . . .

UPDATE: Reader Fred Bartlett says I’m unfair:

Tony Zirkle does not exchange ideas with the National Socialists on a regular basis. Besides, he wasn’t at the meetings where the inflammatory and appalling remarks were made.

You are promulgating a distraction from the real issues. You should be ashamed of yourself!

I stand corrected.

ROGER COHEN offers a nuanced view of biofuels, something that’s been in short supply lately: “I’ll grant that the fashion for biofuels led to excess, and that some farm-to-fuel-plant conversion, particularly in subsidized U.S. and European markets, makes no economic or environmental sense. But biofuels remain very much part of the solution. It just depends which biofuels.”

And this is clearly right: “Right now, the biofuel market is being grossly distorted by subsidies and trade barriers in the United States and the European Union. . . . What sense does it make to have a surplus of environmentally friendly Brazilian sugar-based ethanol with a yield eight times higher than U.S. corn ethanol and zero impact on food prices being kept from an American market by a tariff of 54 cents on a gallon while Iowan corn ethanol gets a subsidy?”

Drop the tariff, drop the subsidies, let the market do it. (Via The Drawn Cutlass).

MORE ON BILL AYERS.